Mark Platt 

Overview 

Marks PhD was earned in the field of Electrochemistry at the University of Manchester in 2004, supervised by Prof Robert A. W. Dryfe. His work entitled “Controlled deposition at the liquid/liquid interface” pioneered the use of template deposition using mesoporous materials at the liquid/liquid interface. His first post-doctoral position was at Pennsylvania State University with Prof Mary. E. Williams (2004 – 2005), where he developed new methods for the conjugation of magnetic nanoparticles into biological systems allowing the use of magnetic fields to manipulate and control the position of tubulin microtubules and facilitate the creation of bio-MEMS devices. Following a period at Cambridge University with Dr Adrian Fisher (2005-2006) investigating microfluidic devices for the creation of copper nanoparticles, he moved to the University of Manchester under Professors Douglas Kell and Philip Day (2006 – 2009) where he joined an interdisciplinary group developing a method capable of both creating and studying DNA-aptamer sequences. Prior to his lectureship at Loughborough he secured independent funding as part of an Intra-European Marie Curie Fellowship (2009-2012) at University College Dublin. Here he developed particle synthesis techniques, and nanopore sensors for the detection of virus’s and bacteria for which he received recognition for leadership in the programme by receiving the award of “Irelands Champions of EU Research 2012”.

Over the past five years as a lecturer at Loughborough, he has built a solid research team, successfully leveraging a second Marie Curie Fellowship, and is part of an exciting €11M H2020 project “TOXI-Triage” (H2020 653409), leading the biological detection of multiplexed assays for Bacteria and small biological particles. The group research 1) the controlled movement and detection of ions, proteins and nanomaterials across nanopore sensors, 2) the use or emulsion droplet reactors for the synthesis of nanomaterials and 3) the fabrication of sensors using additive manufacturing. Through the integration of emerging electroanalytical platforms, aptamer technologies and nanomaterials his research is delivering new analytical methods for healthcare, environmental and materials sensors.

 

Copy of CV - March 2017

Marie Curie Fellow


orcid.org/0000-0002-9195-7216

Current Project students

Postgraduate research projects

Project:   Biosensors

Student: Nigel Lucas

Project:   Epigenetic sensors

Student: Sofia Siati


Group Alumni


2016 - 17

Research Associate 

Dr William Rowe

PhD Student

Chen Hu (Co-supervised with Prof Alfred Tok, NTU Singapore)

Undergraduate research projects

Project:   PADs and Nanopores

Student: James Ayres

Project:   Multiplexed bioassays using TRPS

Student: Tom Hyde

Project:  Turning droplets to metal

Student: Jack Woolley


2015 - 16

PhD Student

Emily-Rose Billinge

MSc research projects

Project: Lateral Flow Assays

Student: Amal Hinai

Undergraduate research projects

Project:   Exploring effects of pH and ionic strength using TRPS

Student: Michael Lickorish

Project:   Use of Emulsion drops to synthesis nanomaterials

Student: Rhushabh Maugi


2014 - 15

Postgraduate research projects

Project:   TRPS for the characterization of materials

Student: Luke Perryman


Undergraduate research projects

Project:   Developing Lateral flow assays for POCT

Student: Chloe King


Erasmus Students

Spring 2015

Student: Ewa Sergott

Project: TRPS student of DNA modified particles


Summer placements

Student: Beth Holton

Project: TRPS studies into protein modified surfaces

Student: Rhushabh Maugi

Project: Emulsion based particle synthesis

2013 - 14

Undergraduate research projects

Project:   Quantification of DNA and proteins in solution using  tunable resistive pulse sensing.

Student: Laura Mayne


MSc research projects

Project:   Exploring the protein-DNA interaction using resistive pulse sensing.

Student: Roja Hadianamrei 


Project:   Characterising particles via TRPS.

Student: Tipmetee Siwapinyoyos


2012 - 13

Undergraduate research projects

Project:   Analyte detection using RPS and aptamer modified beads.

Student: Emma Blundell


Project:   Multicomponent Rods synthesis using template electrodeposition.

Student:  Joey Walker


Project:   ATRP modified superparamagnetic beads.

Student:   Sunil Rajput


Project:   Optimizing the seperation of superparamagnetic beads

Student:   Grace Donaldson

MSc research projects

Project: Synthesis of superparamagnetic beads for detection of DNA
Student: Meaad Fatani

Project: Synthesis of superparmagnetic beads for high affinity protein separation.

Student: Suchanuch Sachdev


Summer Placement

Student: Jess Shiels

Project: Template guided deposition


Spring 2017

The Group 

Dr Emma Blundell (Research associate)

MChem (Hons) Chemistry with Analytical Science 

Whilst completing my final year project investigating resistive pulse sensing for analyte detection and quantification, I became increasingly interested in the field of bionanotechnology. I had always been curious about the applications of nanoparticles in diagnostics and am excited about the emerging possibilities being established in this research group. The novel technology of tunable resistive pulse sensing is of great interest to me as I feel its applications and uses will allow for many new discoveries in nanoscience.  I feel the research being carried out and the incorporation of aptamer development will be greatly beneficial to both the realms of nanotechnology and diagnostics



Laura Mayne (PhD student)

MChem (Hons) Medicinal and Pharmaceutical Chemistry

During my final year project I was investigating the use of resistive pulse sensing to quantify DNA in solution. From this project I became interested in the field of nanotechnology and its various applications. I find the many applications of tunable resistive pulse sensors (TRPS) exciting along with the emerging possibilities of the technology. The use of TRPS and nanoparticles to detect and quantify radionuclides contaminants in solution is an exciting and novel field that I look forward to researching during my PhD.


Sarah Hampson (PhD student)

MChem (HonsChemistry 

After a background in Art and Design (having originally come to university to study Art) I developed a great interest in colour science and UV-visible spectroscopy. My two undergraduate projects studied the spectral and electrochemical behaviour of electrochromic and photochromic systems, with a goal to aid the development of advanced functional dye technologies. Following this, I am now undertaking the design of self-contained, 3D-printed, highly controlled microfluidic flow reactors for uniform nanoparticle synthesis.



Nikita Sachdev (PhD student)

MSc Analytical Chemistry 

Since I was young, science has fascinated me. The study of things at molecular level is very interesting and is always appealing to me. I completed my Bachelor of Science in Chemistry from Thailand. Later, I decided to do my Master of Science in Analytical Chemistry at Loughborough University. The studies here are interesting and challenging at the same time. But most importantly it has made me an independent learner. My MSc. project was about synthesis and separation of superparamagnetic beads under the supervision of Dr. Mark Platt. The instruments used were microfluidics and izon. It was challenging but I really did enjoy doing this project. After completing my master dregree, I took up a part time job as a Chemistry Teacher in Thailand. I realised that one does not truly understand a topic until one starts teaching it. I love teaching but I also want to grow as a scientist. A PhD will enable me to reach my future goals which are doing research and educating. I am really grateful to receive the opportunity and I will give it my best.


Matthew Healey (PhD student) 

MChem (Hons) Chemistry 

Co-supervisor with Dr Sivakumaran (Peterborough Hospital)


















Having originally studied a BA Marketing Management degree at the University of Derby, I went on to complete a retail management scheme for a large supermarket chain. However, a few years ago I decided to pursue my passion for science and enrolled at Loughborough University on a BSc chemistry degree, leading to a MChem in chemistry. Whilst studying for my MChem I developed a fascination with DNA and my final year project focused on the extraction of DNA from the Vernonia plant species, using traditional chemical extraction methods and newer commercial available kits. Following this, I am now undertaking a PhD within the Platt Research Group. The overall goal is to develop a blood assay that can be used to screen for the fatal neurological diseases caused by the prion protein. The project focuses on the use of DNA aptamers and peptides coupled with tunable resistive pulse sensing to overcome this diagnostic challenge. 

Rhush Maugi (PhD student) 

MChem (Hons) Medicinal and Pharmaceutical Chemistry

Whilst studying my undergraduate degree in medicinal and pharmaceutical chemistry, my passion for research in chemistry was ignited. My masters year allowed me to partake in a research project that investigated gold nanoparticles, which captured my attention. Looking at these nanoparticles under a microscope really made me realise that something as small as these particles can have a huge impact in the world. After graduating, I wanted to follow my passion for research by embarking on the journey of studying further via a PhD route.

Marcus Pollard (PhD student) 

BSc (Hons) Chemistry with a Diploma in Industrial Studies

During my undergraduate degree I was able to complete a placement in the Health Innovation & Feasibility team for Reckitt Benckiser. During this placement my desire to push knowledge was cemented and a PhD was the best way to achieve this. I’m passionate about nanopores and nanotechnology as I feel discoveries could genuinely make a difference to someone’s life which is what motivates me. I’m also part of the Centre for Doctoral Training for Embedded Intelligence (CDT-EI) which is a multidisciplinary centre which aims to equip PhD students with the necessary skills to succeed in both business and academia.


 

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